Remember to horn when going around curves on mountainous roads as drivers commonly drive in the middle of the road here. There are a lot of one-way roads in Bali (meant to help traffic flow but it hasn't really turned out that way). If you miss your turn off, you may have to drive quite a distance before being able to turn back. This has resulted in motorbike riders riding a few hundred meters in the wrong direction as a shortcut rather than following traffic flow. Be alert!

It is not recommended to drive at night especially on the road to Gilimanuk where the ferry to Java commences. Truck drivers to and from Java are notorious for overtaking on corners.
You can fill up at any of the many Pertamina's (government's owned oil company) petrol stations or in more remote areas at stalls by the side of the road displaying bottles of clear liquid. The quality may not be as good as that at the petrol station.

One way to beat the traffic is to go by air! There are a few companies that provide helicopters for joy rides or charter, or go by boat. One ingenious individual who wanted to avoid the flooded and traffic jammed Jalan Bypass Ngurah Rai chartered a boat from Benoa Harbour to Nusa Dua. It is all possible in Bali.